In a study performed by Meng et al., it was found that expression of the angiogenic factor VEGFA and its receptor VEGFR2 mRNA and protein was significantly reduced in the gestational diabetes mellitus (GDM) group (p < 0.05) compared to the expression in placentas from normal pregnancies (Meng et al. 2016). The gene discussed is VEGFA; the disease is gestational diabetes.