However, the frequency of BRAF-mutated tumors was only 41%, thus lower than the reported which might be explained by the fact that melanoma patients with BRAF mutations have a worse prognosis, thus a higher risk of mortality compared to patients without BRAF mutations (Davies et al. 2002; Banerji et al. 2008; Edlundh-Rose et al. 2006; Safaee Ardekani et al. 2012). Here, BRAF is linked to melanoma.