Remarkably, compared to control tumours which were KRT8 and pAMPK positive (Fig. 4f, left panels), GPx2 KD tumours contained KRT8/KRT14 positive areas that expressed pAMPK (in the cytosol) and GLUT1 (at the membrane) in same cells (Fig. 4f, right panels). This evidence concerns the gene KRT8 and neoplasm.