Two studies analyzed Flortaucipir (F18-AV-1451) PET data, which is used to investigate tau accumulation, from the Alzheimer’s Disease Neuroimaging Initiative – Department of Defense USA dataset (ADNI-DoD USA); the prospective cohort by Weiner et al. (2022) and the cross-sectional study by Mohamed et al. (2019). Here, MAPT is linked to early-onset autosomal dominant Alzheimer disease.