SIDT1 and lung cancer: Previous studies on mammalian SIDT1 and SIDT2 have implicated them in various biological processes such as glucose and lipid metabolism, immune response, and tumorigenesis, including breast, lung, gastrointestinal, pancreatic and non–small cell lung cancers, but the specific mechanisms are unknown (5, 6, 7, 8, 9, 10, 11, 12, 13).