IGHE and asthma: For the diagnose of ABPA is necessary a set of minimal essential criteria: asthma, immediate cutaneous reactivity to Aspergillus fumigatus, total serum IgE > 1000 ng/mL plus one of the following: elevated specific IgE or IgG-Aspergillus Fumigatus or central bronchiectasis in the absence of distal bronchiectasis.35