SOX11 and mantle cell lymphoma: SOX11 is not expressed in normal B cells and does not have a known function dedicated to B-lymphopoiesis.25, 26, 27 Several lines of evidence have reported an oncogenic role for SOX11 in MCL pathogenesis through the regulation of gene expression2,28, 29, 30, 31 and augmentation of aberrant B-cell receptor signaling.32