When we applied these two gene sets to the in vivo response profiles described in Fig 2 generated for Mtb-infected AMs following high dose infection with mEmerald-H37Rv, we observe that Mtb-infected AMs from scBCG mice up-regulate the IFN-dependent response in vivo, suggesting that the licensing of the IFN-dependent response plays a role in vivo following BCG vaccination (Fig 6B). This evidence concerns the gene IFNA1 and infection.