However, there was a pregnancy-associated increased expression of uromodulin protein in total kidney extract in pregnant Stroke-Prone Spontaneously Hypertensive rats (FC: 1.5, p < 0.0001) and pregnant Wistar Kyoto rats (FC: 1.3, p = 0.005) compared to non-pregnant animals (Fig. 2d). The gene discussed is UMOD; the disease is Stroke.