IL1B and diabetes mellitus: Under high glucose and oxidative stress conditions, like those observed in diabetes, SCs express increased levels of nuclear factor-κβ (NF-κβ), Toll-like receptors (e.g., TLR4) and pro-inflammatory cytokines and chemokines such as TNF-α, IL-6, IL-1β, CXCL9, CXCL10, and CXCL11 [120, 136–138].