The exact expression profiles of OTR in breast tumorsof differentsubtypes and stages remain an active research question; however, OTR-specificnuclear imaging tracers accumulated in breast malignancies in vivo, suggesting that OTR expression is sufficient fortumor-specific targeting, at least in the rodent models employed.127,128,156 More systematic studies investigatingOTR expression across a large panel of breast cancer patient sampleswill be critical in revealing cancer subtypes that display robustOTR overexpression to support tumor imaging and targeted radiotherapy. The gene discussed is OXTR; the disease is neoplasm.