The latter reflects partial relief by l‐NAME of inhibition from S‐nitrosylation at the level of αKGDH since AD‐hiN were shown to manifest increased S‐nitrosylation of αKGDH subunit 1 and its E3 subunit DLD (Figure 1C,D), similar to that found in AD brains (Figure 1A and Table S1, Supporting Information, EXCEL spreadsheet 5, labeled “Unique to AD”). Here, DLD is linked to Alzheimer disease.