In the treatment of platinum-resistant ovarian cancer patients, reports of triple therapy with interstitial implantation radiotherapy combined with immunotherapy and granulocyte-macrophage colony-stimulating factor (GM-CSF) (PRaG for short) are relatively rare.<h4>Case description</h4>Here, we report a patient with oligometastatic platinum-resistant ovarian cancer. Here, CSF2 is linked to ovarian cancer.