As shown in Figure 6G, when reexposed to exogenous TAAs derived from ID8-p53−/−NLRC5+ cells (Ag irrC5), PBMCs derived from parental or NLRC5+ tumor-bearing mice secreted significantly more IFN-γ compared with PBMCs reacting toward Ag irrF3 or the control VSV-N peptide. This evidence concerns the gene NLRC5 and neoplasm.