Further, it was found that the main pathways enriched in both OLP and oral cancer (either early or late stage), were “antigen presentation pathway”; “formation of the cornified envelope”; “antigen processing cross-presentation”; “interleukin-10 signaling”; “collagen chain trimerization”; “neutrophil degranulation” and “non-integrin membrane-ECM interactions”. This evidence concerns the gene IL10 and lip and oral cavity carcinoma.