However, when compared to LH, there were no significant differences in the risk of postoperative complications between the two groups (Biliary Fistula: OR: 0.66, 95% CI: 0.27, 1.59, I2 = 0.000%, P=0.798; Hepatic Failure: OR:0.75, 95%CI: 0.20, 2.79, I2 = 37.7%, P = 0.205; Incision-related Conditions: OR:0.30, 95% CI: 0.06, 1.5, I2 = 0.00%, P = 0.981; Pleural Effusion: OR:1.20, 95% CI: 0.65, 2.23, I2 = 0.00%, P = 0.421; Abdominal Ascites: OR:0.90, 95% CI: 0.44, 1.86, I2 = 0.00%, P = 0.895) (Supplementary Figures S1A–E). Here, PLOD1 is linked to Hepatic failure.