TRIM63 and neoplasm: Although FOR did not recover body weight in the presence of DOX treatment (Figure 3A) or potentiate the tumor weight reduction (Figure 3B), it was able to recover the grip strength and the muscle mass (p<0.05) (Figure 3C–E), in addition to reducing the gene expression of Trim63 (p < 0.01) and Fbxo32 (p < 0.05) (Figure 3F).