For instance, in prostate cancer, Prostate cancer antigen 3 (PCA3), a lncRNA, can form a double-stranded RNA with PRUNE2 (a human homolog of the Drosophila prune gene) to attract ADAR1 binding and exert an editing effect to regulate PRUNE2’s level [86]. The gene discussed is PCA3; the disease is prostate carcinoma.