The research team identified differentially expressed genes between tumor and healthy tissues and selected 3 genes to construct a risk model (ac4C score): collagen type XV alpha 1 chain (COL15A1), glucose-6-phosphate dehydrogenase (G6PD), and tumor protein p53 inducible protein 3 (TP53I3). The gene discussed is G6PD; the disease is neoplasm.