Among hematological malignancies, the role of BTLA polymorphisms in CLL has only been investigated in our study by Karabon et al. The association between ten BTLA SNPs: rs2705511, rs1982809, rs9288952, rs76844316, rs16859633, rs9288953, rs2705535, rs1844089, rs2705565, and rs2633580, and CLL risk was evaluated in 321 patients and 470 HC in the Polish population. Here, BTLA is linked to B-cell chronic lymphocytic leukemia.