Direct observation of i.n. ZPC-738-GFP infection (50 pfu) in fixed whole skull mounts revealed strong suppression of infection in the ONE and OB at 3 dpi in IFNα-treated compared to vehicle-treated mice, which displayed robust ZPC-738-GFP throughout the ONE, OB, and olfactory tract (Fig. 5D). The gene discussed is IFNA1; the disease is infection.