In triple-negative breast cancer, USP29 was recently reported to be phosphorated and activated by cyclin-dependent kinase 1 (CDK1), and then deubiquitinate and stabilize twist family bHLH transcription factor 1 (TWIST1), which is a key regulator of epithelial-mesenchymal transition [24]. Here, TWIST1 is linked to triple-negative breast carcinoma.