In a multivariate regression model (including other variables that have been demonstrated to be associated with a worse prognosis in glioblastoma [i.e., age, extent of resection, presurgical KPS, and MGMT methylation status]), normal levels of circulating androgens upon diagnosis significantly increase the risk of progression (HR 6.346; 95% CI [1.812–22.223]; p = 0.004) (Table 3). Here, MGMT is linked to glioblastoma.