The ROC curve results showed that IL-6 ≥ 6.89pg/mL and HNL ≥ 99.66ng/mL were risk factors for AIS patients with SAP, both of which had good diagnostic value, and the area, sensitivity and specificity under the curve of combined detection of the two indicators were higher than that of single detection. The gene discussed is IL6; the disease is androgen insensitivity syndrome.