In this study, we investigated the potential of preoperative inflammatory serum markers, including Interleukin-6 (IL-6), C-reactive protein (CRP) and Interleukin-8 (IL-8), as biomarkers for long-termn survival in patients with curatively resectable colorectal cancer (CRC) and liver metastases. This evidence concerns the gene CXCL8 and colorectal carcinoma.