Compared with patients in the low C-NLR level group, patients in the high C-NLR level group were older and had a higher heart rate (HR), a higher proportion of NYHA IV patients, a higher prevalence of coronary disease and diabetes, and higher WBC, NEU, LYM, ALT, AST, STB, CB, creatinine, urea nitrogen, BNP, lgBNP, CRP and NLR levels (p < 0.05) but lower DBP, RBC, HB, sodium, albumin (Alb), TC, and eGFR levels, as well as low left ventricular end diastolic volume (LVEDV) and left ventricular end systolic volume (LVESV) (p < 0.05) (Table 1). This evidence concerns the gene NPPB and diabetes mellitus.