PTEN and melanoma: We also examined the migratory effects of the loss of PTEN in human melanoma cells with wild-type PTEN, such as UACC257 and Malme3M cells with the BRAFV600E mutation, SK-MEL-2 cells with the NRASQ61R mutation, MeWo cells with neither the BRAF, NRAS, nor NF1 mutation, and MP41 cells with the GNA11Q209L mutation.