CDR2L and hepatocellular carcinoma: One-way cox analysis was performed on these 33 candidate genes (Fig. 4, Supplementary Table 3), and the results revealed that 7 genes, including CDR2L, were significantly associated with prognostic survival of HCC patients, suggesting these 7 genes may be related to CAFs in HCC and may play an important role in the prognosis of HCC patients.