To test OST-01 in vivo, we injected 0.5 × 106 luciferase-expressing FLT3-ITD+ Molm-13 AML cells (Luc-Molm13 cells) into immunodeficient NSG mice and treated them with either OST-01 or vehicle (ethanol) [1 μL/g, oral gavage, BID] until they achieved a euthanized endpoint (Fig. S4A). This evidence concerns the gene FLT3 and acute myeloid leukemia.