PGR and endometrioid adenocarcinoma: EC is categorized into two types: type I is estrogen-dependent, mainly including grades I and II endometrioid adenocarcinoma and estrogen-progesterone receptor-positive endometrial cancer, with a 5-year overall survival (OS) of 85%; type II is estrogen-independent, and the pathological types are grade III endometrioid carcinoma, serous carcinoma, clear cell carcinoma, undifferentiated carcinoma and carcinosarcoma, with a 5-year OS of less than 55% [2].