RETREG1 and acute kidney injury: Immunoblot assays revealed a decline in DDRGK1, UFL1, UFM1, FAM134B, and TEX264 levels accompanied by an increase in calnexin (CANX), an ER marker, in CI-AKI kidney lysates, indicating a decrease in DDRGK1–UFL1-mediated ER-phagy in this model (Fig. 2E–I, Fig. S1).