The cyclic guanosine monophosphate (GMP)‐adenosine monophosphate synthase (cGAS)‐stimulator of interferon genes (STING) pathway has been identified as a critical role in initiating innate and adaptive anti‐tumor immune responses.[1] Serving as a sensor protein for virus DNA, the cGAS enzyme can sense exogenous DNA fragments in the cytoplasm and catalyze adenylate triphosphate and guanosine triphosphate into 2′,3′‐cyclic GMP‐adenosine monophosphate (cGAMP) to activate STING. This evidence concerns the gene STING1 and neoplasm.