In an alternative approach to determining the gradient of CHD risk per unit difference in genetically predicted Lp(a)-apoB and LDL-apoB, we examined the relationship of apoB to incident CHD risk by ventile of ‘Lp(a)’ PGS (Figure 3, Panel B), and by ventile of ‘LDL’ PGS (Panel A). This evidence concerns the gene LPA and coronary artery disorder.