Likewise, use of polygenic scores to rank subjects according to difference in Lp(a)-apoB vs. difference in LDL-apoB revealed a greater hazard ratio for CHD per 50nmol/l apoB for the ‘Lp(a)’ cluster (1.47 [95%CI:1.36-1.58]) compared to the ‘LDL’ cluster (1.04 [95%CI:1.02-1.05]). This evidence concerns the gene APOB and coronary artery disorder.