Lipoprotein (a) (Lp(a)) - an LDL-like particle containing apolipoprotein B (apoB) with an additional protein, apolipoprotein (a) (apo(a)) - has been identified as a causal factor for coronary heart disease (CHD) based initially on epidemiological findings and most recently on genetic studies 1–3. The gene discussed is APOB; the disease is coronary artery disorder.