Specifically, we selected all common genetic variants (minor allele frequency of >0.01) within ±50 Kbp flanking regions at the IL32 locus on chromosome 16 (n = 194) and tested the association with alanine transaminase (ALT) level, a marker of liver damage associated with fatty liver, in a total of 425,671 European participants from the UK Biobank (Figure 7A).29 This evidence concerns the gene GPT and fatty liver disease.