GPT and liver disorder: Next, we examined the phenotype associated with rs76580947 minor allele and found that carriers of the variant had lower ALT (beta = −0.02, p = 9.9 × 10−13) and that they also consistently showed lower aspartate aminotransferase (AST) (beta = −0.02, p = 3.2 × 10−10), reduced risk of severe liver disease (adjusted odds ratio, 0.82; 95% confidence interval, 0.71–0.96; p = 0.013), and lower total cholesterol (beta = −0.01; p = 0.009) (Table S1).