The expression levels of DVL1, DVL3 and FZD3 mRNAs were significantly lower in the nasal polyps than in the turbinates, while those of FZD6, PRICKLE1, PRICKLE2, VANGL1 and VANGL2 mRNAs were not statistically different between the two tissues. The gene discussed is VANGL2; the disease is Nasal polyposis.