GPT and kidney disorder: In addition, M Afarideh et al. found a decreasing tendency of ALT in T2DM with DR (23.9 ± 10.9 U/L vs. 28.7 ± 23.0 U/L, p < 0.05) and T2DM with nephropathy (26.7 ± 14.1 U/L vs. 28.7 ± 23.0 U/L, p > 0.05) compared with T2DM patients free of microvascular complications [10].