Besides, WEE1 inhibition effectively reversed resistance to BRAF inhibitors (Haarberg et al. 2013; Sharma et al. 2013) and AURKA inhibitor (MLN8237) in HPV- HNSCC (head and neck squamous cell carcinoma (Lee et al. 2019). The gene discussed is AURKA; the disease is head and neck squamous cell carcinoma.