WEE1 and central nervous system cancer: Similarly, heightened expression or increased activity of WEE1 was observed in glioma (Mueller et al. 2014; Music et al. 2016), liver cancer models (Masaki et al. 2000, 2003), medulloblastoma (Harris et al. 2014), seminoma (Mir et al. 2010), breast cancer, and osteosarcoma (PosthumaDeBoer et al. 2011; Wang et al. 2011).