Y. Zhou and his colleagues found that calycosin (100 μM) inhibited SK‐0V‐3 cancer cell growth, proliferation and induced apoptosis via upregulating production of cleaved caspase‐3, cleaved caspase‐9, Bax/Bcl‐2 ratio and downregulating expression of Bcl‐2, pro‐caspase‐3, pro‐caspase‐9 signaling.98 This evidence concerns the gene BAX and cancer.