reported that in ER‐positive breast cancer cells, calycosin inhibits migration and invasion of breast cancer cells with a dose of 150 μM via downregulation of Rab27B (member of the RAS oncogene family), VEGF (vascular endothelial growth factor), and β‐catenin allude anti‐cancer activity of calycosin.65 Here, RAB27B is linked to breast carcinoma.