AKT1 and cancer: Calycosin exerted anti‐cancer activity in vitro model IGF‐1R mediated cell proliferation by controlling PI3K/Akt signaling pathways and of calycosin‐mediated apoptosis with inhibiting cell invasion by targeting SIRT1 activator which induces activation of AMPK‐induced inhibition of Akt/mTOR axis in HT29 cell line.50