STAT3 and colorectal carcinoma: In another recent study, about calycosin (100 μM) work on IGF‐1 stimulates growth and metastasis in CRC cell lines, where it upregulates BAX/Bcl‐2, caspase 3, 9, β‐catenin, BATF2 via STAT3 was with suppression of FOXM1 through STAT1 & NF‐κβ pathways.71