However, certain indications warrant cranial magnetic resonance imaging (MRI) in girls with precocious puberty, such as cases under six years of age, the presence of neurologic findings between the ages of 6-8 years, rapidly progressing puberty, and an exaggerated response to the luteinizing hormone-releasing hormone (LHRH) test (10). This evidence concerns the gene GNRH1 and precocious puberty.