PRC2 inhibition by EPZ6438 or MAK683 led to tumor regression in xenograft mouse models.[23, 24] To investigate whether BMP‐ACVR1 signaling is activated by PRC2 inhibition in vivo, we examined the tumor xenograft of WSU‐DLCL2 with vehicle or oral dosing of MAK683. The gene discussed is ACVR1; the disease is neoplasm.