QZJFD has been found to improve acute radiation pneumonia and the incidence of pulmonary fibrosis in patients with advanced lung tumor via reducing the levels of tumor necrosis factor-α (TNF-α), endothelin (ET), connective tissue growth factor (CTGF) and platelet-derived growth factor (PDGF) in plasma [5, 12]. The gene discussed is CCN2; the disease is pulmonary fibrosis.