FOSL1 and cancer: Their functions align more with the inflammatory cancer‐associated fibroblasts, particularly the apCAFs characteristics.[106, 107, 108] pEMT, CAF1, and CAF2 cells undergo a transition from epithelial keratinization to extracellular matrix remodeling and immune response regulation through the expression of various TFs such as FOSL1, TCF4, and SPI1.