Notably, the HSIL organoids retained the capacity to self‐renew, organize, and differentiate to form mature squamous stratified organoids similar to healthy tissues[48] with basal p63 + Ki67+ stem cells, p63 + Ki67‐parabasal, and p63‐ Ki67‐KRT13 + differentiated cells, whereas the SqCa organoids mainly contained P63 + Ki67 + tumor cells. This evidence concerns the gene TP63 and neoplasm.