Li et al. [21] found that upregulated lncRNA Sox2ot in plasma-derived EVs regulated the expression of SRY-box transcription factor 2 (Sox2) by sponging the miR-200 family, thereby promoting the metastasis of pancreatic ductal adenocarcinoma (PDAC). The gene discussed is SOX2; the disease is pancreatic ductal adenocarcinoma.