Importantly, our data showed that p‐S6 was reduced, Ki67 was increased in tumors from LAMTOR1 K151R KI mice compared to that in WT mice (Figure 6I; Figure S7F, Supporting Information), which is consistent with the findings of Marta Brandt et al.[37] that mTORC1 inactivation promotes AOM/DSS‐induced CRC. This evidence concerns the gene LAMTOR1 and infectious otitis media.