LDHB and familial pancreatic carcinoma: In addition to LDHA, Lactate Dehydrogenase B (LDHB), the converting enzyme of lactate to pyruvate [13–15], as well as members of Heat Shock (“stress”) Protein (HSP) families with anti-apoptotic properties are frequently overexpressed in a broad range of different cancer cell types including breast cancer, colorectal carcinoma, lung and pancreatic cancer cells [16].