The P value was statistically significant among the following ten clinical features: age (WMD = 1.78, P = 0.026), hypertension (OR = 0.54,, P < 0.001), diabetes (OR = 0.42, P < 0.001), albumin (WMD = − 0.26, P < 0.001), urinary protein level (WMD = 0.76, P = 0.001), urinary protein ≥ 1.5 g/d (OR = 1.98, P < 0.001), lambda − chain value (WMD = 29.02, P < 0.001), abnormal free light-chain ratio (OR = 4.16, P = 0.002), bone marrow puncture rate (OR = 5.11, P = 0.019), and abnormal bone marrow outcome rate (OR = 9.63, P = 0.005). The gene discussed is ALB; the disease is diabetes mellitus.