We individually assessed pooled effect sizes for 19 clinical characteristics (age, sex, hypertension, diabetes, albumin, hemoglobin, serum creatinine, estimated glomerular filtration rate, complement C3, complement C4, low complement C3 ratio, urinary protein level, urinary protein ≥ 1.5 g/d, hematuria, kappa-chain value, lambda-chain value, abnormal free light-chain ratio (kappa / lambda chain), bone marrow puncture rate, and abnormal bone marrow outcome rate). This evidence concerns the gene C3 and diabetes mellitus.