In this study, patients with MGRS were older and had fewer underlying diseases (diabetes and hypertension), lower serum albumin, more urinary protein (including proteinuria ≥ 1.5 g/d ratio), more abnormal free light-chain ratios, and more abnormal findings from the bone marrow than those of patients with MG and non-MIg-associated nephropathy [8, 9, 13, 14]. The gene discussed is ALB; the disease is Hypertension.