Here, we found CCL20 was the most down-regulated cytokine after ABLIM1 silence in RNA-seq (Table S1), and CCL20 secretion was enhanced after ABLIM1 overexpression, indicating NF-κB-induced CCL20 might be involved in the growth and metastasis of CRC modulated by ABLIM1. Here, NFKB1 is linked to colorectal carcinoma.