We also specifically demonstrate that administration of either a ketogenic diet (KDp or KDt) or an oral ketone body supplementation (EKB) can reliably induce systemic ketosis, significantly reduce aortic wall CCR2 and pro-inflammatory cytokines, increase collagen content in the AAA media, and promote an MMP balance that minimizes elastin degradation (Fig. 5). Here, CCR2 is linked to triple-A syndrome.