Therefore, we hypothesized that nutritional ketosis, either in the form of a ketogenic diet (KD) or exogenous ketone body (EKB) supplementation, can impact CCR2-mediated inflammation and improve MMP balance in aortic tissue to reduce the risk of AAA progression, aortic wall inflammation, ECM content, and the incidence of AAA rupture. Here, CCR2 is linked to triple-A syndrome.