LY96 and leukemia: PARPi and ATRi - mediated accumulation of γH2AX+ AML-MD2 cells and reduction of cell survival was accompanied by induction of differentiation (increased of CD14+/CD11b+, CD11c+, and HLA-DR+ living cells) (Supplementary Fig. S3) which might contribute to strong anti-leukemia activity of the combination [8].